ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESI....FIRO..CY..TRBGCZEEHU..SK....................................JDIM360 Ver 2.15 (14 Jul 2008) - 2999001/01988397CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120120215W154deBibliographieenBibliographyfrBibliographieEP08014241.7200312192008080820090519enenen435079 P20021219US465435 P20030424US2012021520120720081105200845201109142011372011041320120215201207G01N 33/68 20060101AFI20080926BHEP C07D 263/56 20060101ALI20080926BHEP A61P 25/28 20060101ALI20080926BHEP A61K 31/423 20060101ALI20080926BHEP deZUSAMMENSETZUNGEN UND VERWENDUNGEN ZUR STABILISIERUNG VON TRANSTHYRETIN UND ZUR HEMMUNG VON TRANSTHYRETIN-FEHLFALTUNGenCOMPOSITIONS AND USES FOR STABILISING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDINGfrCOMPOSITIONS ET UTILISATIONS POUR STABILISER LA TRANSTHYRETINE ET POUR INHIBER UN MAUVAIS REPLIEMENT DE LA TRANSTHYRETINEPETERSON S A ET AL: "Inhibiting Transhyretin Conformational Changes That Lead To Amyloid Fibril Formation" PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, vol. 95, 1 October 1998 (1998-10-01), pages 12956-12960, XP002988070 ISSN: 0027-8424MIROY G J ET AL: "INHIBITING TRANSTHYRETIN AMYLOID FIBRIL FORMATION VIA PROTEIN STABILIZATION" PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, vol. 93, no. 26, 1 December 1996 (1996-12-01), pages 15051-15056, XP002070247 ISSN: 0027-8424KELLEY J W: "The Environment Dependency of Protein Folding Best Explains Prion and Amyloid Diseases" PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, vol. 95, 1 February 1998 (1998-02-01), pages 930-932, XP002988069 ISSN: 0027-8424LASHUEL H A ET AL: "New Class Of Inhibitors Of Amyloid-beta Fibril Formation" JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,; US, vol. 277, no. 45, 1 November 2002 (2002-11-01), pages 42881-42890, XP002988068 ISSN: 0021-925803813782.415878212003121910180989.5232565120100928Kelly, Jeffery W.8110 El Paseo Grande, No. 407La Jolla, CA 92037USSEKIJIMA, YoshikiRoyal Garden Sawamura H-11 3-8-25-8 SawamuraMatsumoto 390-0877JPThe Scripps Research Institute101046342J100714PCEPT110550 North Torrey Pines RoadLa Jolla, CA 92037USWeber, Martinet al101202900Jones Day Prinzregentenstraße 1180538 MünchenDEATBEBGCHCYCZDEDKEEESFIFRGBGRHUIEITLILUMCNLPTROSESISKTR20081105200845