(19)

(11)

EP 1 991 238 A1

(12)

(43) Date of publication: 19.11.2008 Bulletin 2008/47 (21) Application number: 07797159.6 (22) Date of filing: 09.03.2007

(51) International Patent Classification (IPC):  A61K 31/70(2006.01) A61K 31/715(2006.01) (86) International application number: PCT/US2007/063701 (87) International publication number: WO 2007/130738 (15.11.2007 Gazette 2007/46)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR (30) Priority: 09.03.2006 US 780770 P (71) Applicant: Polytechnic University Brooklyn, NY 11201 (US)	(72) Inventors: GROSS, Richard A. Plainview, NY 11803 (US) SHAH, Vishal Plainsboro, NY 08536 (US) (74) Representative: Aulich, Martin  Meissner, Bolte & Partner GbR Hollerallee 73 28209 Bremen 28209 Bremen (DE)