(19)

(11)

EP 1 996 275 A2

(12)

(88) Date of publication A3: 21.02.2008 (43) Date of publication: 03.12.2008 Bulletin 2008/49 (21) Application number: 07752914.7 (22) Date of filing: 09.03.2007

(51) International Patent Classification (IPC):  A61M 31/00(2006.01) (86) International application number: PCT/US2007/006248 (87) International publication number: WO 2007/106453 (20.09.2007 Gazette 2007/38)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR (30) Priority: 10.03.2006 US 781049 P (71) Applicant: ALZA Corporation Mountain View, CA 94039 (US)	(72) Inventors: PANCHULA, Martin, A. Mountain View, CA 94043 (US) TONG, Ling-kang Mountain View, CA 94043 (US) (74) Representative: Lloyd, John Scott  Edwards Angell Palmer & Dodge Innovations LLP 10 Carlton Crescent GB-Southampton SO15 2EZ GB-Southampton SO15 2EZ (GB)