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(11)

EP 1 996 937 A2

(12)

(88) Date of publication A3: 29.11.2007 (43) Date of publication: 03.12.2008 Bulletin 2008/49 (21) Application number: 07752549.1 (22) Date of filing: 06.03.2007

(51) International Patent Classification (IPC):  G01N 33/53(2006.01) C12N 5/06(2006.01) G01N 33/567(2006.01) (86) International application number: PCT/US2007/005857 (87) International publication number: WO 2007/103455 (13.09.2007 Gazette 2007/37)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR (30) Priority: 06.03.2006 US 743410 P 21.03.2006 US 743622 P 27.09.2006 US 528927 27.09.2006 US 528950 (71) Applicant: Amunix, Inc. Mountain View, CA 94043 (US)

(72) Inventors: SCHELLENBERGER, Volker Palo Alto, CA 94303 (US) STEMMER, Willem P. Los Gatos, CA 95030 (US) WANG, Chia-Wei Santa Clara, CA 95051 (US) SCHOLLE, Michael D. Mountain View, CA 94043 (US) POPKOV, Mikhail San Diego, CA 92131 (US) GORDON, Nathaniel C. Campbell, CA 95008 (US) CRAMERI, Andreas Los Altos Hills, CA 94022 (US) (74) Representative: Kremer, Simon Mark et al Mewburn Ellis LLP York House, 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)