| (84) |
Designated Contracting States: |
|
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE
SI SK TR |
| (30) |
Priority: |
23.03.2006 JP 2006080691 13.02.2007 JP 2007032777
|
| (43) |
Date of publication of application: |
|
24.12.2008 Bulletin 2008/52 |
| (60) |
Divisional application: |
|
11184021.1 / 2404596 |
| (73) |
Proprietor: TMRC Co., Ltd. |
|
Tokyo 105-0013 (JP) |
|
| (72) |
Inventor: |
|
- EKIMOTO, Hisao
Tokyo 115-0042 (JP)
|
| (74) |
Representative: Jones, Helen M.M. et al |
|
Gill Jennings & Every LLP
The Broadgate Tower
20 Primrose Street London EC2A 2ES London EC2A 2ES (GB) |
| (56) |
References cited: :
EP-A- 0 396 184 WO-A2-2005/027842 JP-A- 07 215 882 JP-A- 2000 506 489 JP-A- 2005 512 961
|
WO-A2-2004/093856 WO-A2-2005/039490 JP-A- 11 012 175 JP-A- 2004 528 316
|
|
| |
|
|
- DEBRUYNE F M J ET AL: "Ketoconazole high dose (H.D.) in advanced prostatic cancer
: A comparison of two dosage regimens" JOURNAL OF STEROID BIOCHEMISTRY, PERGAMON PRESS
PLC, GB, vol. 28, 1 January 1987 (1987-01-01), page 81, XP023420229 ISSN: 0022-4731
[retrieved on 1987-01-01]
- HO A D ET AL: "Combination of low-dose cytarabine and 13-cis retinoic acid in the
treatment of myelodysplastic syndromes" LEUKEMIA RESEARCH, NEW YORK,NY, US, vol. 11,
no. 11, 1 January 1987 (1987-01-01), pages 1041-1044, XP022921542 ISSN: 0145-2126
[retrieved on 1987-01-01]
- "986 PUBLICATION Clinical study of combining arsenic trioxide (As2O3), all-trans retinoic
acid (ATRA) and idarubicin (IDA) for induction therapy on the patients with relapsed
acute promyelocytic leukemia(APL)" EUROPEAN JOURNAL OF CANCER. SUPPLEMENT, PERGAMON,
OXFORD, GB, vol. 3, no. 2, 1 October 2005 (2005-10-01), page 284, XP005133100 ISSN:
1359-6349
- GANSLMAYER MARION ET AL: "The combination of tamoxifen and 9cis retinoic acid exerts
overadditive anti-tumoral efficacy in rat hepatocellular carcinoma" JOURNAL OF HEPATOLOGY,
vol. 40, no. 6, June 2004 (2004-06), pages 952-956, XP009118834 ISSN: 0168-8278
- LEUNG MUN-FAI ET AL: "The combined differentiating effect of retinoic acid and vincristine
on acute promyelocytic leukemia" LEUKEMIA RESEARCH, vol. 21, no. 1, 1997, pages 81-84,
XP009118839 ISSN: 0145-2126
- JOZAN SUZANNE ET AL: "Cytotoxic effect of interferon-alpha2a in combination with all-trans
retinoic acid or cisplatin in human ovarian carcinoma cell lines" ANTI-CANCER DRUGS,
vol. 9, no. 3, March 1998 (1998-03), pages 229-238, XP009118840 ISSN: 0959-4973
- GANSLMAYER MARION ET AL: "Combined tamoxifen and retinoids affect intratumoral apoptosis
rate in a rat HCC model" GASTROENTEROLOGY, vol. 126, no. 4, Suppl. 2, April 2004 (2004-04),
page A597, XP009118835 & DIGESTIVE DISEASE WEEK/105TH ANNUAL MEETING OF THE AMERICAN-GASTROENTEROLOGICAL-ASSOCIATION;
NEW ORLEANS, LA, USA; MAY 16 20, 2004 ISSN: 0016-5085
- CLERICI CARLO ET AL: "Treatment with all-trans retinoic acid plus tamoxifen and vitamin
E in advanced hepatocellular carcinoma" ANTICANCER RESEARCH, vol. 24, no. 2C, March
2004 (2004-03), pages 1255-1260, XP009118836 ISSN: 0250-7005
- ANZANO M A ET AL: "CHEMOPREVENTION OF MAMMARY CARCINOGENESIS IN THE RAT: COMBINED
USE OF RALOXIFENE AND /-CIS-RETINOIC ACID" JOURNAL OF THE NATIONAL CANCER INSTITUTE,
OXFORD UNIVERSITY PRESS, GB, vol. 88, no. 2, 17 January 1996 (1996-01-17), pages 123-125,
XP002054376 ISSN: 0027-8874
- EMI N.: 'Kyusei Zen Kotsudui Kyusei Hakketsubyo ni Taisuru Shinki Chiryoho' BESSATSU
IGAKU NO AYUMI 15 September 2005, pages 446 - 448, XP003017982
- SAHARA N. ET AL.: 'Am-80, A Hissan ni yoru Kyusei Zen Kotsudui Kyusei Hakketsubyo
no Chiryo' RINSHOI vol. 31, no. 12, 10 December 2005, pages 1920 - 1923, XP003017983
- NANRI T. ET AL.: 'Kyusei Zen Kotsuduisei Hakketsubyo (Actepromyelocytic leukemia)'
HEMATOLOGY & ONCOLOGY vol. 52, no. 1, 28 January 2006, pages 10 - 19, XP003017984
- KAWAKITA T. ET AL.: 'Kyusei Zen Kotsudui Kyusei Hakketsubyo Chiryo no Saikin no Hatten
(Recent advances in the treatment of acute promyclocytic leukemia)' BIO CHIMICA vol.
20, no. 13, 10 December 2005, pages 1153 - 1158, XP003017985
- YANADA M. ET AL.: '<<Hyojunteki Chiryoho to sono Mondaiten>>, Kyusei Zen Kotsuduikyusei
Hakketsubyo' NAIKA vol. 92, no. 3, 01 September 2003, pages 464 - 469, XP003017986
- KAGECHIKA H.: 'Gosei Tetinoids to sonorRinsho Oyo (Synthetic tetionoids and their
clinical applications)' HEMATOLOGY & ONCOLOGY vol. 51, no. 3, 28 September 2005, pages
277 - 282, XP003017987
- TALLMAN M.S. ET AL.: 'Retinoids in Cancer Treatment' J. CLIN. PHARMACOL. vol. 32,
no. 10, October 1992, pages 868 - 888, XP001000254
- KUROKI T. ET AL.: 'Koganzei no Sayo Kiko' IWANAMI KOZA GENDAI IGAKU NO KISO 10 DAI
7 KAI HAIHON SAIBO ZOSHOKU TO GAN, KABUSHIKI KAISHA IWANAMI SHOTEN 29 June 1999, pages
199 - 212, XP003017988
- KALEMKERIAN G.P. ET AL.: 'Activity of Fenretinide plus chemotherapeutic agents in
small-cell lung cancer cell lines' CANCER CHEMOTHER. PHARMACOL. vol. 43, no. 2, February
1999, pages 145 - 150, XP002950455
- FORMELLI F. ET AL.: 'Synthetic retinoid Fenretinide is effective against a human ovarian
carcinoma xenograft and potentiates Cisplatin activity' CANCER RESEARCH vol. 53, no.
22, 15 November 1993, pages 5374 - 5376, XP008130036
- SHUDO K. ET AL.: 'kan Shuyo Chiroyozai toshite no Gosei Retinoid Kaihatsu-TAK-101
no Kiso to Rinsho eno Tenbo (Synthetic retinoid development as hepatic tumor therapeutic
agent. Basis of TAC-101 and prospect of its clinical application)' THE JOURNAL OF
CLINICAL SCIENCE vol. 33, no. 6, June 1997, pages 721 - 727, XP003017990
|
|