(19)

(11)

EP 2 010 194 A2

(12)

(88) Date of publication A3: 29.11.2007 (43) Date of publication: 07.01.2009 Bulletin 2009/02 (21) Application number: 07753123.4 (22) Date of filing: 14.03.2007

(51) International Patent Classification (IPC):  A61K 36/00(2006.01) (86) International application number: PCT/US2007/006473 (87) International publication number: WO 2007/109071 (27.09.2007 Gazette 2007/39)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 15.03.2006 US 782960 P (71) Applicant: Rutgers, The State University of New Jersey New Brunswick, NJ 08901 (US)	(72) Inventors: HO, Chi-tang East Brunswick, NJ 08816 (US) LI, Shiming Glastonbury, CT 06033 (US) PAN, Min-hsiung Zuoying District, kaohsiung City, 813 (CN) LO, Chih-yu Somerset, NJ 08873 (US) DUSHENKOV, Slavik Fort Lee, NJ 07024 (US) (74) Representative: Steinecke, Peter et al MÜLLER FOTTNER STEINECKE Rechtsanwälte Patentanwälte P.O. Box 31 01 40 80102 München 80102 München (DE)