ATBECHDEDKESFR..GRITLILUNLSEMCPTIESILTLVFIRO..CY..TRBGCZEEHUPLSK....IS..MT..........................*JJDIM360 Ver 1.28 (29 Oct 2014) - 2999001/02016182CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120150902W184deBibliographieenBibliographyfrBibliographieEP07732664.3200705042008112020091009enenen060938320060511GB062105120061023GB2015090220153620090121200904201507082015282014082520150902201536C12N 15/869 20060101AFI20080215BHEP deMUTANTES HSV, MATERIALIEN UND VERFAHREN ZUR ERZEUGUNG DES MUTANTEN HSVenMUTANT HSV, MATERIALS AND METHODS FOR GENERATION OF MUTANT HSVfrVIRUS HERPÈS SIMPLEX MUTANT ET MATÉRIAUX ET PROCÉDÉS PERMETTANT DE LE GÉNÉRERGAGE P J ET AL: "A CELL-FREE RECOMBINATION SYSTEM FOR SITE-SPECIFIC INTEGRATION OF MULTIGENIC SHUTTLE PLASMIDS INTO THE HERPES SIMPLEX VIRUS TYPE 1 GENOME" JOURNAL OF VIROLOGY, NEW YORK, US, US, vol. 66, no. 9, 1 September 1992 (1992-09-01), pages 5509-5515, XP000568386 ISSN: 0022-538XTERADA K ET AL: "Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor models" GENE THERAPY, vol. 13, no. 8, April 2006 (2006-04), pages 705-714, XP002448244 ISSN: 0969-7128KRISKY D M ET AL: "Rapid method for construction of recombinant HSV gene transfer vectors" GENE THERAPY, MACMILLAN PRESS LTD., BASINGSTOKE, GB, vol. 10, no. 4, October 1997 (1997-10), pages 1120-1125, XP002079298 ISSN: 0969-7128LANDY A: "DYNAMIC, STRUCTURAL, AND REGULATORY ASPECTS OF LAMBDA SITE-SPECIFIC RECOMBINATION" ANNUAL REVIEW OF BIOCHEMISTRY, PALTO ALTO, CA, US, vol. 58, 1989, pages 913-948, XP008008244 ISSN: 0066-4154SHEN Y ET AL: "HERPES SIMPLEX VIRUS 1 (HSV-1) FOR CANCER TREATMENT" CANCER GENE THERAPY, NORWALK, CT, US, vol. 13, 7 April 2006 (2006-04-07), pages 975-992, XP008071389 ISSN: 0929-1903SCHMEISSER FALKO ET AL: "Incorporation of a lambda phage recombination system and EGFP detection to simplify mutagenesis of Herpes simplex virus bacterial artificial chromosomes" BMC BIOTECHNOLOGY, vol. 7, May 2007 (2007-05), page Article No.: 22, XP002448126 ISSN: 1472-6750NAKANO MASAKAZU ET AL: "Production of viral vectors using recombinase-mediated cassette exchange", 20050101; 20050000, vol. 33, no. 8, 1 January 2005 (2005-01-01), page e76, XP002454932,NAKANO MASAKAZU ET AL: "Production of viral vectors using recombinase-mediated cassette exchange", 20050101; 20050000, vol. 33, no. 8, 1 January 2005 (2005-01-01), page E76, XP002454932,CONNER, JoeCrusade Laboratories Limited PO Box 1716Glasgow, Strathclyde G51 4WFGBVirttu Biologics Limited101282040RIC/MP6594865F1 House, Road Four Winsford Industrial EstateWinsford Cheshire CW7 3QNGBClegg, Richard Ianet al100055382Mewburn Ellis LLPCity Tower 40 Basinghall Street London EC2V 5DEGBATBEBGCHCYCZDEDKEEESFIFRGRHUIEISITLILTLULVMCMTNLPLPTROSESISKTRGB200700163120070504enWO20071321692007112220074720090121200904