ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIRO..CY..TRBGCZEEHUPLSK....IS..........JDIM360 Ver 2.15 (14 Jul 2008) - 1990850/0 1999001/02019142CORRECTED EUROPEAN PATENT APPLICATIONA9A320090513W172deBibliographieenBibliographyfrBibliographieEP08013335.820051205enenen632567 P20041203US690160 P20050614US710999 P20050825US728737 P20051021US200905132009202009012820090520090513200920C12N 15/82 20060101AFI20081211BHEP C07K 14/415 20060101ALI20081211BHEP deelF-5A Isoformen und deren VerwendungenenIsoforms of elF-5A and methods of using samefrIsoformes de elF-5A et leurs procédés d'utilisationNONE05852821.7182498220051205Senesco Technologies, Inc.03974930N1881 EP/1 S3303 George St., Ste 420New Brunswick, NJ 08901USThompson, John, E.901 University Ave. E.Waterloo Ontario N2K 4N1CAMcNamara, Linda4-105 Golden Eagle RoadWaterloo Ontario N2V 1C3CAWu, Wendy118 Moore Ave. S.Waterloo, Ontario N2J 1X2CAWang, Tzann-Wei607 Salzburg DriveWaterloo, Ontario N2V 2L5CAVossius & Partner00103241Siebertstraße 481675 MünchenDEATBEBGCHCYCZDEDKEEESFIFRGBGRHUIEISITLILTLULVMCNLPLPTROSESISKTR20090401200914

The present invention relates to unique isoforms of eukaryotic initiation Factor 5A ("eIF-5A"): senescence-induced eIF-5A; wounding/pathogen induced eIF-5A; stress eIF-5A and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase ("DHS"), polynucleotides that encode DHS, and methods involving modulating the expression of DHS.