(19)

(11)

EP 2 019 688 A2

(12)

(88) Date of publication A3: 14.02.2008 (43) Date of publication: 04.02.2009 Bulletin 2009/06 (21) Application number: 07797567.0 (22) Date of filing: 18.05.2007

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) A61K 38/00(2006.01) C12N 5/00(2006.01) A61K 31/70(2006.01) G01N 33/53(2006.01) C12Q 1/68(2006.01) (86) International application number: PCT/US2007/069211 (87) International publication number: WO 2007/137149 (29.11.2007 Gazette 2007/48)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 22.05.2006 US 747886 P 01.06.2006 US 810456 P (71) Applicant: Velcura Therapeutics, Inc. Ann Arbor MI 48108 (US)	(72) Inventor: LONG, Michael Northville, MI 48167 (US) (74) Representative: Dehmel, Albrecht  Dehmel & Bettenhausen Patentanwälte, Herzogspitalstrasse 11 80331 München 80331 München (DE)