(19)

(11)

EP 2 029 117 A2

(12)

(43) Date of publication: 04.03.2009 Bulletin 2009/10 (21) Application number: 08742580.7 (22) Date of filing: 03.04.2008

(51) International Patent Classification (IPC):  A61K 9/24(2006.01) A61K 45/06(2006.01) A61K 9/26(2006.01) (86) International application number: PCT/US2008/004429 (87) International publication number: WO 2008/124081 (16.10.2008 Gazette 2008/42)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 04.04.2007 US 922031 P 31.05.2007 US 932613 P 21.03.2008 US 70563 P (71) Applicant: Teva Pharmaceutical Industries Ltd. 49131 Petah Tiqva (IL)	(72) Inventors: ZALIT, Ilan Rosh Ha Ayin (IL) ZADOK, Uri 46361 Herzliyya (IL) (74) Representative: Russell, Tim et al D Young & Co 120 Holborn London EC1N 2DY London EC1N 2DY (GB)