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(11)

EP 2 029 535 A1

(12)

(43) Date of publication: 04.03.2009 Bulletin 2009/10 (21) Application number: 07748167.9 (22) Date of filing: 24.05.2007

(51) International Patent Classification (IPC):  C07D 209/46(2006.01) A61K 31/4192(2006.01) A61P 1/00(2006.01) A61P 25/04(2006.01) A61P 9/00(2006.01) C07D 401/06(2006.01) C07D 405/14(2006.01) A61K 31/4035(2006.01) A61K 31/444(2006.01) A61P 25/00(2006.01) A61P 35/00(2006.01) C07D 401/04(2006.01) C07D 405/06(2006.01) (86) International application number: PCT/SE2007/000503 (87) International publication number: WO 2007/139464 (06.12.2007 Gazette 2007/49)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 26.05.2006 US 803242 P (71) Applicant: AstraZeneca AB 151 85 Södertälje (SE)	(72) Inventors: CHENG, Yun-Xing Montreal, Québec H4S 1Z9 (CA) TOMASZEWSKI, Miroslaw Montreal, Québec H4S 1Z9 (CA) YANG, Hua Verdun, Québec H3E 1B8 (CA)