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(11)

EP 2 029 548 A1

(12)

(43) Date of publication: 04.03.2009 Bulletin 2009/10 (21) Application number: 07729614.3 (22) Date of filing: 29.05.2007

(51) International Patent Classification (IPC):  C07D 231/18(2006.01) A61P 25/30(2006.01) A61K 31/4155(2006.01) (86) International application number: PCT/EP2007/055192 (87) International publication number: WO 2007/138050 (06.12.2007 Gazette 2007/49)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 31.05.2006 US 809367 P 31.05.2006 EP 06114752 (71) Applicant: Solvay Pharmaceuticals B.V. 1381 CP Weesp (NL)	(72) Inventors: LANGE, Josephus H.M. 1381 CP Weesp (NL) KRUSE, Cornelis G. 1381 CP Weesp (NL) VAN VLIET, Bernard J. 1381 CP Weesp (NL) (74) Representative: Verhage, Marinus  Octrooibureau Zoan B.V. P.O. Box 140 1380 AC Weesp 1380 AC Weesp (NL)