(19)
(11) EP 2 029 743 A1

(12)

(43) Date of publication:
04.03.2009 Bulletin 2009/10

(21) Application number: 07795515.1

(22) Date of filing: 31.05.2007
(51) International Patent Classification (IPC): 
C12N 15/09(2006.01)
A61K 38/00(2006.01)
 A61K 31/70(2006.01)
(86) International application number:
PCT/US2007/012787
(87) International publication number:
WO 2008/030283 (13.03.2008 Gazette 2008/11)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK RS

(30) Priority: 31.05.2006 US 443920
19.10.2006 US 852761 P

(71) Applicants:
  • Beth Israel Deaconess Medical Center, Inc.
    Boston, MA 02215 (US)
  • The Hospital for Sick Children Research Institute
    Toronto, Ontario M5G 1X8 (CA)

(72) Inventors:
  • KARUMANCHI, S. Ananth
    Chestnut Hill, MA 02467 (US)
  • SUKHATME, Vikas P.
    Newton, MA 02459 (US)
  • TOPORSIAN, Mourad
    Toronto, Ontario M5G 1H4 (CA)
  • LETARTE, Michelle V.
    Toronto, Ontario M4K 2Z7 (CA)

(74) Representative: Baldock, Sharon Claire 
BOULT WADE TENNANT Verulam Gardens 70 Gray's Inn Road
London WC1X 8BT
London WC1X 8BT (GB)

   


(54) METHODS OF DIAGNOSING AND TREATING COMPLICATIONS OF PREGNANCY