(19)
(11) EP 2 032 599 A2

(12)

(88) Date of publication A3:
03.04.2008

(43) Date of publication:
11.03.2009 Bulletin 2009/11

(21) Application number: 07730060.6

(22) Date of filing: 11.06.2007
(51) International Patent Classification (IPC): 
C07K 14/47(2006.01)
 C12N 15/09(2006.01)
(86) International application number:
PCT/EP2007/055726
(87) International publication number:
WO 2007/141346 (13.12.2007 Gazette 2007/50)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK RS

(30) Priority: 09.06.2006 GB 0611463

(71) Applicant: Novartis AG
4056 Basel (CH)

(72) Inventors:
  • CHATTERJEE, Sandipan
    Somerville, Massachusetts 02144 (US)
  • DEV, Kumlesh K
    Windle Building, Cork (IE)
  • KUHN, Rainer R
    CH-4125 Riehen (CH)
  • SIVASANKARAN, Rajeev
    Acton, Massachusetts 01720 (US)

(74) Representative: Kassow, Anders 
Novartis Pharma AG Patent Department
4002 Basel
4002 Basel (CH)

   


(54) GENES REGULATING INTRACELLULAR CHOLESTEROL TRAFFICKING AS TARGETS FOR TREATMENT OF CHOLESTEROL-RELATED DISEASES