(19)
(11) EP 2 035 039 A2

(12)

(88) Date of publication A3:
02.05.2008

(43) Date of publication:
18.03.2009 Bulletin 2009/12

(21) Application number: 07795651.4

(22) Date of filing: 31.05.2007
(51) International Patent Classification (IPC): 
A61K 39/395(2006.01)
(86) International application number:
PCT/US2007/013028
(87) International publication number:
WO 2007/145862 (21.12.2007 Gazette 2007/51)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK RS

(30) Priority: 05.06.2006 US 811234 P

(71) Applicants:
  • Genentech, Inc.
    South San Francisco CA 94080-4990 (US)
  • F. Hoffmann-La Roche AG
    4002 Basel (CH)

(72) Inventors:
  • AMLER, Lukas, C.
    Foster City, CA 94404 (US)
  • MOECKS, Joachim
    68167 Mannheim (DE)
  • RABBEE, Nusrat
    Richmond, CA 94804 (US)
  • STRAUSS, Andreas
    82377 Penzberg (DE)

(74) Representative: Walton, Seán Malcolm et al
Mewburn Ellis LLP 33 Gutter Lane
London EC2V 8AS
London EC2V 8AS (GB)

   


(54) EXTENDING SURVIVAL OF CANCER PATIENTS WITH ELEVATED LEVELS OF EGF OR TGF-ALPHA