(19)

(11)

EP 2 035 404 A1

(12)

(43) Date of publication: 18.03.2009 Bulletin 2009/12 (21) Application number: 07733321.9 (22) Date of filing: 21.06.2007

(51) International Patent Classification (IPC):  C07D 333/20(2006.01) A61P 25/00(2006.01) A61K 31/381(2006.01) (86) International application number: PCT/GB2007/002325 (87) International publication number: WO 2007/148103 (27.12.2007 Gazette 2007/52)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 23.06.2006 GB 0612506 (71) Applicants: Arrow International Limited Valetta, VLT 08 (MT) Chongqing Shenghuaxi Pharmaceutical Co., Ltd. Nan-an Chongqing (CN)	(72) Inventors: JIANG, Wei, Ping Chongqing 401-336 (CN) JIA, Chun, Rong Chongqing 401-336 (CN) (74) Representative: Schlich, George William et al Schlich & Co 34 New Road Littlehampton West Sussex BN17 5AT Littlehampton West Sussex BN17 5AT (GB)