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EP 2 035 441 A1

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(43) Date of publication: 18.03.2009 Bulletin 2009/12 (21) Application number: 06785533.8 (22) Date of filing: 23.06.2006

(51) International Patent Classification (IPC):  C07H 23/00(2006.01) G01N 33/567(2006.01) C12P 19/42(2006.01) (86) International application number: PCT/US2006/024685 (87) International publication number: WO 2007/149098 (27.12.2007 Gazette 2007/52)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (71) Applicant: QOL Medical, LLC Vero Beach, FL 32963 (US)	(72) Inventors: QUAY, Steven, C. Seattle, WA 98122 (US) GO, Zenaida, O. Clifton, NY 07013 (US) APRILE, Peter, C. East Northport, NY 11731-4713 (US) SILENO, Antony, P. Brookhaven Hamlet, NY 11719 (US) (74) Representative: Ritter, Thomas Kurt et al Jones Day Prinzregentenstraße 11 80538 München 80538 München (DE)