(19)

(11)

EP 2 044 083 A1

(12)

(43) Date of publication: 08.04.2009 Bulletin 2009/15 (21) Application number: 07799544.7 (22) Date of filing: 12.07.2007

(51) International Patent Classification (IPC):  C07D 495/04(2006.01) A61P 31/12(2006.01) A61K 31/407(2006.01) (86) International application number: PCT/US2007/073391 (87) International publication number: WO 2008/008912 (17.01.2008 Gazette 2008/03)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 14.07.2006 US 831040 P (71) Applicant: GENELABS TECHNOLOGIES, INC. Redwood City, CA 94063 (US)

(72) Inventors: SCHMITZ, Franz Ulrich Mill Valley, California 94941 (US) ROBERTS, Christopher Don Belmont, California 94002 (US) GRIFFITH, Ronald Conrad Escondido, California 92029 (US) BOTYANSZKI, Janos Fremont, California 94539 (US) PHAM, Son Minh San Francisco, California 94127 (US) (74) Representative: Wibbelmann, Jobst  Wuesthoff & Wuesthoff Patent- und Rechtsanwälte Schweigerstrasse 2 81541 München 81541 München (DE)