(19)

(11)

EP 2 046 302 A2

(12)

(43) Date of publication: 15.04.2009 Bulletin 2009/16 (21) Application number: 06851345.6 (22) Date of filing: 08.05.2006

(51) International Patent Classification (IPC):  A61K 9/22(2006.01) (86) International application number: PCT/US2006/009201 (87) International publication number: WO 2009/023006 (19.02.2009 Gazette 2009/08)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK YU (71) Applicant: McNeil-PPC, Inc. Skillman, NJ 08558 (US)	(72) Inventor: SOWDEN, Harry, S. Glenside, PA 19038 (US) (74) Representative: Kirsch, Susan Edith et al Carpmaels & Ransford 43-45 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)