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(11)

EP 2 046 325 A1

(12)

(43) Date of publication: 15.04.2009 Bulletin 2009/16 (21) Application number: 07812924.4 (22) Date of filing: 13.07.2007

(51) International Patent Classification (IPC):  A61K 31/352(2006.01) A61K 36/48(2006.01) A61K 31/353(2006.01) A61P 5/30(2006.01) (86) International application number: PCT/US2007/073505 (87) International publication number: WO 2008/016768 (07.02.2008 Gazette 2008/06)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 02.08.2006 US 819849 P 14.02.2007 US 889920 P 11.06.2007 US 943190 P (71) Applicant: Brinton, Roberta, Diaz Rancho Palos Verdes, CA 90275 (US)	(72) Inventor: ZHAO, Liqin Los Angeles, CA 09934 (US) (74) Representative: HOFFMANN EITLE  Patent- und Rechtsanwälte Arabellastrasse 4 81925 München 81925 München (DE)