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(11)

EP 2 049 105 A2

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(43) Date of publication: 22.04.2009 Bulletin 2009/17 (21) Application number: 07797049.9 (22) Date of filing: 27.07.2007

(51) International Patent Classification (IPC):  A61K 31/407(2006.01) A61P 31/04(2006.01) A61N 5/00(2006.01) (86) International application number: PCT/US2007/016951 (87) International publication number: WO 2009/014524 (29.01.2009 Gazette 2009/05)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 27.07.2006 US 833836 P 25.07.2007 US 880974 (71) Applicant: CeramOptec GmbH 53121 Bonn (DE)	(72) Inventors: NIFANTIEV, Nikolay, E. Moscow B-593, 117593 (RU) GITTER, Burkhard D-07743 Jena (DE) YASHUNSKY, Dmitri, V. Moscow 119270 (RU)