(19)

(11)

EP 2 049 135 A2

(12)

(88) Date of publication A3: 21.02.2008 (43) Date of publication: 22.04.2009 Bulletin 2009/17 (21) Application number: 07784522.0 (22) Date of filing: 22.06.2007

(51) International Patent Classification (IPC):  A61K 38/00(2006.01) (86) International application number: PCT/US2007/071942 (87) International publication number: WO 2007/150049 (27.12.2007 Gazette 2007/52)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 22.06.2006 US 805540 P (71) Applicant: Agennix Incorporated Houston, TX 77046 (US)	(72) Inventors: VARADHACHARY, Atul Houston, TX 77401 (US) PETRAK, Karel Houston, TX 77077 (US) BLEZINGER, Paul Pledger, TX 77468 (US) (74) Representative: Woods, Geoffrey Corlett et al J.A. KEMP & CO. 14 South Square Gray's Inn London WC1R 5JJ Gray's Inn London WC1R 5JJ (GB)