(19)
(11) EP 2 054 414 A2

(12)

(88) Date of publication A3:
22.05.2008

(43) Date of publication:
06.05.2009 Bulletin 2009/19

(21) Application number: 07840855.6

(22) Date of filing: 10.08.2007
(51) International Patent Classification (IPC): 
C07D 471/20(2006.01)
C07D 487/20(2006.01)
A61K 31/519(2006.01)
C07D 487/04(2006.01)
C07D 498/04(2006.01)
A61P 25/28(2006.01)
(86) International application number:
PCT/US2007/075690
(87) International publication number:
WO 2008/022024 (21.02.2008 Gazette 2008/08)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

(30) Priority: 17.08.2006 US 838357 P

(71) Applicant: Wyeth
Madison, NJ 07940 (US)

(72) Inventors:
  • MALAMAS, Michael, Sotirios
    Jamison, Pennsylvania 18929 (US)
  • BARNES, Keith, Douglas
    Rexford, New York 12148 (US)
  • JOHNSON, Matthew, Robert
    Guilderland, New York 12084 (US)

(74) Representative: Talbott, Dawn Jacqueline 
Wyeth Pharmaceuticals, Huntercombe Lane South, Taplow
Maidenhead, Berkshire SL6 0PH
Maidenhead, Berkshire SL6 0PH (GB)

   


(54) IMIDAZOLE AMINES AS INHIBITORS OF BETA-SECRETASE