(19)
(11) EP 2 056 852 A2

(12)

(88) Date of publication A3:
09.04.2009

(43) Date of publication:
13.05.2009 Bulletin 2009/20

(21) Application number: 07798210.6

(22) Date of filing: 07.06.2007
(51) International Patent Classification (IPC): 
A61K 38/02(2006.01)
C07H 21/00(2006.01)
C12N 1/00(2006.01)
C12P 21/00(2006.01)
A61P 19/00(2006.01)
C07K 2/00(2006.01)
C12N 15/63(2006.01)
(86) International application number:
PCT/US2007/070584
(87) International publication number:
WO 2008/014054 (31.01.2008 Gazette 2008/05)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK RS

(30) Priority: 27.07.2006 US 820538 P

(71) Applicant: Centocor, Inc.
Malvern, PA 19355 (US)

(72) Inventors:
  • AMEGADZIE, Bernard
    Phoenixville, PA 19460 (US)
  • CUNNINGHAM, Mark R.
    Kennett Square, PA 19348 (US)
  • DORAI, Haimanti
    Exton, PA 19341 (US)
  • LUO, Jeffrey
    Malvern, PA 19355 (US)
  • MILLS, Juliane
    Wallingford, PA 19086 (US)
  • SWENCKI-UNDERWOOD, Bethany
    Chester Springs, PA 19425 (US)

(74) Representative: Marshall, Cameron John 
Carpmaels & Ransford 43-45 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) BMP-7 VARIANT COMPOSITIONS, METHODS AND USES