CATALYTIC ASYMMETRIC SYNTHESIS OF PRIMARY AMINES VIA BORANE REDUCTION OF OXIME ETHERS USING SPIROBORATE ESTERS - Patent 2061748

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EP 2 061 748 A2

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(88)	Date of publication A3:
	22.05.2008

(43)	Date of publication:
	27.05.2009 Bulletin 2009/22

(21)	Application number: 07814214.8

(22)	Date of filing: 17.08.2007

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International Patent Classification (IPC):

C07C 209/52^(2006.01)

(86)	International application number:
	PCT/US2007/076195

(87)	International publication number:
	WO 2008/027740 (06.03.2008 Gazette 2008/10)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
	Designated Extension States:
	AL BA HR MK RS

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Priority:

29.08.2006 US 841147 P

(71)	Applicant: Office Of Intellectual Property And Technology
	San Juan PR 00926-1117 (US)

(72)	Inventors:
	DE JESUS, Melvin Humacoa PR 00791 (US) ORTIZ-MARCIALES, Margarita Humacao PR 00791 (US) STEPANENKO, Viatcheslav Humacao, PR 00791 (US) HUANG, Xiaogen Humacao, PR 00791 (US) HUANG, Kun Humacao, PR 00791 (US) FRANCISCO, Merced Humacao, PR 00791 (US)

(74)	Representative: Isenbruck, Günter
	Isenbruck Bösl Hörschler Wichmann Huhn LLP Patentanwälte Theodor-Heuss-Anlage 12 68165 Mannheim 68165 Mannheim (DE)

(54)	CATALYTIC ASYMMETRIC SYNTHESIS OF PRIMARY AMINES VIA BORANE REDUCTION OF OXIME ETHERS USING SPIROBORATE ESTERS