(19)
(11) EP 2 064 195 A2

(12)

(88) Date of publication A3:
02.10.2008

(43) Date of publication:
03.06.2009 Bulletin 2009/23

(21) Application number: 07868800.9

(22) Date of filing: 20.11.2007
(51) International Patent Classification (IPC): 
C07D 263/57(2006.01)
A61P 15/00(2006.01)
 A61K 31/423(2006.01)
(86) International application number:
PCT/US2007/085226
(87) International publication number:
WO 2008/064217 (29.05.2008 Gazette 2008/22)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK RS

(30) Priority: 21.11.2006 US 860415 P
21.11.2006 US 860317 P
21.11.2006 US 860318 P
21.11.2006 US 860352 P
21.11.2006 US 860248 P
21.11.2006 US 860265 P
21.11.2006 US 860253 P
21.11.2006 US 860246 P

(71) Applicant: Wyeth
Madison, NJ 07940 (US)

(72) Inventors:
  • KRISHNAN, Mahesh K.
    Stony Point, NY 10980 (US)
  • GHORAB, Mohamed
    Edison, NJ 08817 (US)
  • CARSON, Rolland W.
    Tomkins Cove, NY 10986 (US)
  • HASAN, Shamim
    East Elmhurst, NY 11370 (US)
  • NAGI, Arwinder
    Thiells, NY 10984 (US)
  • TADAYON, Abdolsamad
    Kirkland H9J 4B8 (CA)
  • IERA, Silvio
    Montreal H2B 2P4 (CA)
  • MIRMEHRABI, Mahmoud
    Laval H7R 6B7 (CA)

(74) Representative: Talbott, Dawn Jacqueline 
Wyeth Pharmaceuticals, Huntercombe Lane South, Taplow
Maidenhead, Berkshire SL6 0PH
Maidenhead, Berkshire SL6 0PH (GB)

   


(54) CRYSTAL FORMS OF 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL AND PHARMACEUTICAL FORMULATIONS THEREOF