(19)

(11)

EP 2 066 338 A2

(12)

(88) Date of publication A3: 12.06.2008 (43) Date of publication: 10.06.2009 Bulletin 2009/24 (21) Application number: 07825260.8 (22) Date of filing: 04.10.2007

(51) International Patent Classification (IPC):  A61K 38/25(2006.01) (86) International application number: PCT/IB2007/002934 (87) International publication number: WO 2008/041106 (10.04.2008 Gazette 2008/15)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR (30) Priority: 05.10.2006 IT MI20061917 (71) Applicant: Università Degli Studi Di Milano - Bicocca 20126 Milano (IT)

(72) Inventors: LOCATELLI, Vittorio I-20021 Bollate (MI) (IT) TORSELLO, Antonio, Biagio I-20091 Bresso (MI) (IT) BRESCIANI, Elena I-20060 Pozzuolo Martesana (MI) (IT) BULGARELLI, Ilaria I-20100 Milano (IT) TAMIAZZO, Laura I-20053 Muggio' (MI) (IT) RAVELLI, Monica I-24060 Tavernola Bergamasca (BG) (IT) (74) Representative: Minoja, Fabrizio  Bianchetti Bracco Minoja S.r.l. Via Plinio, 63 20129 Milano 20129 Milano (IT)