(19)

(11)

EP 2 068 714 A2

(12)

(88) Date of publication A3: 23.10.2008 (43) Date of publication: 17.06.2009 Bulletin 2009/25 (21) Application number: 07841365.5 (22) Date of filing: 24.08.2007

(51) International Patent Classification (IPC):  A61B 6/00(2006.01) (86) International application number: PCT/US2007/076813 (87) International publication number: WO 2008/025006 (28.02.2008 Gazette 2008/09)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 24.08.2006 US 840247 P (71) Applicant: Xenogen Corporation Alameda, CA 94501 (US)	(72) Inventors: XU, Heng Alameda, California 94501 (US) RICE, Bradley W. Danville, California 94506 (US) (74) Representative: Alton, Andrew  Urquhart-Dykes & Lord LLP Tower North Central Merrion Way Leeds LS2 8PA Leeds LS2 8PA (GB)