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(11)

EP 2 069 383 A2

(12)

(43) Date of publication: 17.06.2009 Bulletin 2009/25 (21) Application number: 08771400.2 (22) Date of filing: 18.06.2008

(51) International Patent Classification (IPC):  C07J 1/00(2006.01) C07J 13/00(2006.01) A61P 3/04(2006.01) C07J 9/00(2006.01) A61K 31/575(2006.01) A61Q 19/06(2006.01) (86) International application number: PCT/US2008/067391 (87) International publication number: WO 2008/157635 (24.12.2008 Gazette 2008/52)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR Designated Extension States: AL BA MK RS (30) Priority: 19.06.2007 US 945035 P 20.08.2007 US 956875 P 21.02.2008 US 35339 25.04.2008 GB 0807615 16.05.2008 US 153446 (71) Applicant: Kythera Biopharmaceuticals, Inc. Calabasas, CA 91301 (US)

(72) Inventors: MORIARTY, Robert M. Michiana Shores, Indiana 46360-1126 (US) DAVID, Nathaniel E. Los Angeles, California 90046 (US) MAHMOOD, Nadir Ahmeduddin Calabasas, California 91302 (US) PRASAD, Achampeta Rathan Hyderabad 500 007 (IN) SWARINGEN, Roy A., Jr. Durham, North Carolina 27712 (US) REID, John Gregory Niskayuma, New York 12309 (US) SAHOO, Akhila Kumar Orissa (IN) (74) Representative: Sexton, Jane Helen et al J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)