(19)

(11)

EP 2 077 845 A2

(12)

(88) Date of publication A3: 02.10.2008 (43) Date of publication: 15.07.2009 Bulletin 2009/29 (21) Application number: 07821862.5 (22) Date of filing: 25.10.2007

(51) International Patent Classification (IPC):  A61K 31/529(2006.01) A61P 35/00(2006.01) (86) International application number: PCT/EP2007/061499 (87) International publication number: WO 2008/049902 (02.05.2008 Gazette 2008/18)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 27.10.2006 EP 06123056 27.10.2006 US 863198 P 28.09.2007 US 976210 P (71) Applicant: Janssen Pharmaceutica NV 2340 Beerse (BE)	(72) Inventors: PERERA, Timothy Pietro Suren 2340 Beerse (BE) VERSELE, Matthias Luc A. 2340 Beerse (BE) PAGE, Martin John 2340 Beerse (BE) (74) Representative: Vandersteen, Pieter et al Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse 2340 Beerse (BE)