(19)

(11)

EP 2 079 704 A2

(12)

(88) Date of publication A3: 18.12.2008 (43) Date of publication: 22.07.2009 Bulletin 2009/30 (21) Application number: 07755933.4 (22) Date of filing: 24.04.2007

(51) International Patent Classification (IPC):  C07D 233/00(2006.01) C07D 487/04(2006.01) C07D 235/02(2006.01) C07D 487/06(2006.01) (86) International application number: PCT/US2007/009862 (87) International publication number: WO 2007/127173 (08.11.2007 Gazette 2007/45)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 25.04.2006 US 794525 P (71) Applicants: Rutgers, The State University of New Jersey New Brunswick, NJ 08903 (US) Lavoie, Edmond J. Princeton Junction, NJ 08550 (US) Rice, Joseph E. East Windsor, NJ 08520 (US) Liu, Leroy Fong Bridgewater, NJ 08807 (US)

(72) Inventors: LAVOIE, Edmond, J. NJ 08550 (US) RICE, Joseph, E. NJ 08520 (US) LIU, Leroy, F. NJ 08807 (US) (74) Representative: Office Freylinger  P.O. Box 48 8001 Strassen 8001 Strassen (LU)