(19)

(11)

EP 2 082 227 A1

(12)

(43) Date of publication: 29.07.2009 Bulletin 2009/31 (21) Application number: 07818427.2 (22) Date of filing: 19.09.2007

(51) International Patent Classification (IPC):  G01N 33/50(2006.01) G01N 33/574(2006.01) (86) International application number: PCT/EP2007/008343 (87) International publication number: WO 2008/034645 (27.03.2008 Gazette 2008/13)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR (30) Priority: 19.09.2006 GB 0618429 (71) Applicant: ISTITUTO SUPERIORE DI SANITA' 00161 Roma (IT)	(72) Inventor: MARCHIANO, Ruggero De Maria I-00161 Roma (IT) (74) Representative: Lord, Hilton David et al Marks & Clerk LLP 90 Long Acre London WC2E 9RA London WC2E 9RA (GB)