(19)
(11) EP 2 084 269 A2

(12)

(88) Date of publication A3:
10.07.2008

(43) Date of publication:
05.08.2009 Bulletin 2009/32

(21) Application number: 07847234.7

(22) Date of filing: 20.11.2007
(51) International Patent Classification (IPC): 
C12N 5/10(2006.01)
C12N 5/06(2006.01)
(86) International application number:
PCT/EP2007/062597
(87) International publication number:
WO 2008/061995 (29.05.2008 Gazette 2008/22)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK RS

(30) Priority: 20.11.2006 EP 06124427

(71) Applicant: Octagene GmbH
82152 Martinsried (DE)

(72) Inventors:
  • SCHRÖDER, Carola
    82061 Neuried (DE)
  • CASADEMUNT, Elisabeth
    81241 München (DE)
  • BJÖRNSTRUP, Kim
    8835 Feusisberg (CH)

(74) Representative: Schreiber, Christoph 
Patentanwälte von Kreisler Selting Werner Deichmannhaus am Dom Bahnhofsvorplatz 1
50667 Köln
50667 Köln (DE)

   


(54) GENETIC ABLATION OF THE PRP GENE CELLS USING A TARGETED PROMOTER TRAP STRATEGY FOR PRODUCTION OF SERUM-FREE RECOMBINANT PROTEINS AS THERAPEUTICALS