(19)
(11) EP 2 086 939 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
22.06.2011 Bulletin 2011/25

(45) Mention of the grant of the patent:
28.07.2010 Bulletin 2010/30

(21) Application number: 07824375.5

(22) Date of filing: 31.10.2007
(51) International Patent Classification (IPC): 
C07D 213/82(2006.01)
C07D 401/12(2006.01)
C07D 413/04(2006.01)
A61K 31/444(2006.01)
 C07D 401/04(2006.01)
C07D 401/14(2006.01)
A61K 31/44(2006.01)
A61K 31/4439(2006.01)
(86) International application number:
PCT/GB2007/004131
(87) International publication number:
WO 2008/053194 (08.05.2008 Gazette 2008/19)

(54)

PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS

PYRIDINCARBOXAMIDE ALS 11-BETA-HSD1-INHIBITOREN

CARBOXAMIDES DE PYRIDINE EN TANT QU'INHIBITEURS DE L'11-BETA-HSD1

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK RS

(30) Priority: 03.11.2006 US 864303 P
03.11.2006 US 864247 P

(43) Date of publication of application:
12.08.2009 Bulletin 2009/33

(60) Divisional application:
10163730.4 / 2233480

(73) Proprietor: AstraZeneca AB
151 85 Södertälje (SE)

(72) Inventors:
  • MCCOULL, William
    Cheshire SK10 4TG (GB)
  • PACKER, Martin
    Cheshire SK10 4TG (GB)
  • SCOTT, James Stewart
    Cheshire SK10 4TG (GB)
  • WHITTAMORE, Paul Robert Owen
    Cheshire SK10 4TG (GB)


(56) References cited: : 
WO-A-2004/065351
WO-A-2005/054200
 WO-A-2004/089896
WO-A-2008/012532
   
  • BARF T ET AL: "Recent progress in 11-[beta]-hydroxysteroid dehydrogenase type 1 (11-[beta]-HSD1) inhibitor development" DRUGS OF THE FUTURE, BARCELONA, ES, vol. 31, no. 3, 1 March 2006 (2006-03-01), pages 231-243, XP002424785 ISSN: 0377-8282
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).