(19)
(11) EP 2 089 376 A1

(12)

(43) Date of publication:
19.08.2009 Bulletin 2009/34

(21) Application number: 07863900.2

(22) Date of filing: 05.11.2007
(51) International Patent Classification (IPC): 
C07D 401/04(2006.01)
A61P 25/28(2006.01)
A61K 31/506(2006.01)
(86) International application number:
PCT/US2007/083619
(87) International publication number:
WO 2008/058068 (15.05.2008 Gazette 2008/20)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

(30) Priority: 07.11.2006 US 857453 P

(71) Applicant: Lexicon Pharmaceuticals, Inc.
The Woodlands, TX 77381 (US)

(72) Inventors:
  • BARBOSA, Joseph
    Lambertville, NJ 08530 (US)
  • BI, Yingzhi
    Plainsboro, NJ 08536 (US)
  • FINK, Cynthia Anne
    Lebanon, NJ 08833 (US)
  • GREEN, Michael Alan
    Easton, PA 18040 (US)
  • WANG, Jian Cheng
    Dallas, TX 75252 (US)

(74) Representative: Duxbury, Stephen et al
Arnold & Siedsma Pettenkoferstrasse 37
80336 München
80336 München (DE)

   


(54) (R)-PHENYL(HETEROCYCLE)METHANOL-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS OF THEIR USE