(19)

(11)

EP 2 089 419 A2

(12)

(88) Date of publication A3: 19.06.2008 (43) Date of publication: 19.08.2009 Bulletin 2009/34 (21) Application number: 07824323.5 (22) Date of filing: 26.10.2007

(51) International Patent Classification (IPC):  C07K 5/09(2006.01) C07K 14/47(2006.01) A61K 38/07(2006.01) C07K 5/11(2006.01) A61K 38/06(2006.01) A61K 38/17(2006.01) (86) International application number: PCT/GB2007/004079 (87) International publication number: WO 2008/050133 (02.05.2008 Gazette 2008/18)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR (30) Priority: 27.10.2006 US 854694 P (71) Applicant: Zapaloid Limited Cambridge CB4 0DP (GB)	(72) Inventors: ZURDO, Jesus Cambridgeshire CB22 4AT (GB) FOWLER, Susan Cambridgeshire CB22 4AT (GB) GIRALT, Ernest 08028 Barcelona (ES) TEIXIDO, Meritxell 08028 Barcelona (ES) CARULLA, Natalia 08028 Barcelona (ES) (74) Representative: Sutcliffe, Nicholas Robert et al Mewburn Ellis LLP 33 Gutter Lane London EC2V 8AS London EC2V 8AS (GB)