(19)

(11)

EP 2 091 907 A1

(12)

(43) Date of publication: 26.08.2009 Bulletin 2009/35 (21) Application number: 07857333.4 (22) Date of filing: 10.12.2007

(51) International Patent Classification (IPC):  C07C 51/41(2006.01) C07C 59/08(2006.01) A61K 8/365(2006.01) C07C 51/42(2006.01) A61Q 11/00(2006.01) (86) International application number: PCT/EP2007/063613 (87) International publication number: WO 2008/071659 (19.06.2008 Gazette 2008/25)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR (30) Priority: 14.12.2006 EP 06126103 (71) Applicant: Purac Biochem N.V. 4206 AC Gorinchem (NL)	(72) Inventors: VORAGE, Marcus Johannus Anthonius Wilhemus 9458 TC Balloo (NL) KLEIN, Kees Jan Blair, Nebraska 680008 (US) (74) Representative: Beetz, Tom  De Vries & Metman Overschiestraat 180 1062 XK Amsterdam 1062 XK Amsterdam (NL)