(19)
(11) EP 2 091 969 A2

(12)

(88) Date of publication A3:
04.12.2008

(43) Date of publication:
26.08.2009 Bulletin 2009/35

(21) Application number: 07812601.8

(22) Date of filing: 03.07.2007
(51) International Patent Classification (IPC): 
C07K 16/00(2006.01)
A61K 39/395(2006.01)
C12P 21/08(2006.01)
C07K 1/00(2006.01)
(86) International application number:
PCT/US2007/072771
(87) International publication number:
WO 2008/057634 (15.05.2008 Gazette 2008/20)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

(30) Priority: 26.10.2006 WO PCT/US2006/041791
03.04.2007 WO PCT/US2007/008396

(71) Applicant: The Rockfeller University
New York, NY 10021-6399 (US)

(72) Inventors:
  • NIMMERJAHN, Falk
    New York, NY 10021 (US)
  • KANEKO, Yoshikatsu
    New York, NY 10021 (US)
  • RAVETCH, Jeffrey V.
    New York, NY 10022 (US)

(74) Representative: Schmidt, Karsten et al
Albihns GmbH Bayerstrasse 83
80335 München
80335 München (DE)

   


(54) POLYPEPTIDES WITH ENHANCED ANTI-INFLAMMATORY AND DECREASED CYTOTOXIC PROPERTIES AND RELATING METHODS