(19)
(11) EP 2 099 364 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
03.04.2019 Bulletin 2019/14

(45) Mention of the grant of the patent:
20.02.2019 Bulletin 2019/08

(21) Application number: 07866306.9

(22) Date of filing: 21.12.2007
(51) International Patent Classification (IPC): 
A61B 8/00(2006.01)
(86) International application number:
PCT/EP2007/064501
(87) International publication number:
WO 2008/074889 (26.06.2008 Gazette 2008/26)

(54)

DETECTION OF THE DETACHMENT OF IMMOBILIZED CONTRAST AGENT IN MEDICAL IMAGING APPLICATIONS

DETEKTION DER ABLÖSUNG EINES IMMOBILISIERTEN KONTRASTMITTELS BEI MEDIZINISCHEN BILDGEBUNGSANWENDUNGEN

DÉTECTION DU DÉCOLLEMENT D'UN AGENT DE CONTRASTE IMMOBILISÉ DANS DES APPLICATIONS D'IMAGERIE MÉDICALE

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

(30) Priority: 21.12.2006 EP 06126850

(43) Date of publication of application:
16.09.2009 Bulletin 2009/38

(73) Proprietor: Bracco Suisse SA
6814 Cadempino (CH)

(72) Inventors:
  • FRINKING, Peter
    1228 Genève (CH)
  • MESSAGER, Tristan
    1228 Genève (CH)
  • ARDITI, Marcel
    1203 Genèva (CH)
  • ROGNIN, Nicolas
    1228 Genève (CH)

(74) Representative: Pezzoli, Ennio et al
c/o Maccalli & Pezzoli S.r.l. Via Settembrini 40
20124 Milano
20124 Milano (IT)


(56) References cited: : 
EP-A- 1 568 323
US-A1- 2002 165 454
 US-A- 5 456 255
US-B1- 6 740 039
   
  • LINDNER J R ED - YUHAS D E ET AL INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS: "Targeted ultrasound contrast agents: diagnostic and therapeutic potential" 2001 IEEE ULTRASONICS SYMPOSIUM PROCEEDINGS. ATLANTA, GA, OCT. 7 - 10, 2001, IEEE ULTRASONICS SYMPOSIUM PROCEEDINGS, NEW YORK, NY : IEEE, US, vol. VOL. 2 OF 2, 7 October 2001 (2001-10-07), pages 1695-1703, XP010584839 ISBN: 0-7803-7177-1
  • LANZA G M ET AL: "TARGETED ULTRASONIC CONTRAST AGENTS FOR MOLECULAR IMAGING AND THERAPY" PROGRESS IN CARDIOVASCULAR DISEASES, SAUNDERS, PHILADELPHIA, PA, US, vol. 44, no. 1, July 2001 (2001-07), pages 13-31, XP008034236 ISSN: 0033-0620 cited in the application & GREGORY E.R. WELLER; ERXIONG LU; MELISSA M. CSIKARI; ALEXANDER L. KLIBANOV; DAVID FISCHER; WILLIAM R. WAGNER: "Ultrasound Imaging of Acute Cardiac Transplant Rejection With Microbubbles Targeted to Intercellular Adhesion Molecule-1" CIRCULATION, vol. 108, 30 June 2003 (2003-06-30), pages 218-224, XP002380571
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).