| (84) |
Designated Contracting States: |
|
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE
SI SK TR |
| (30) |
Priority: |
17.06.2005 US 691920 P
|
| (43) |
Date of publication of application: |
|
16.09.2009 Bulletin 2009/38 |
| (60) |
Divisional application: |
|
12162951.3 / 2505205 |
| (62) |
Application number of the earlier application in accordance with Art. 76 EPC: |
|
06785127.9 / 1909819 |
| (73) |
Proprietor: ImClone LLC |
|
New York, NY 10016 (US) |
|
| (72) |
Inventors: |
|
- Loizos, Nick
Staten Island, NY 10306 (US)
- Huber, Jim
Scotch Plains, NJ 07076 (US)
|
| (74) |
Representative: Kent, Lindsey Ruth et al |
|
Eli Lilly and Company Limited
Lilly Research Center
Erl Wood Manor
Sunninghill Road
Windlesham
Surrey GU20 6PH
Windlesham
Surrey GU20 6PH (GB) |
| (56) |
References cited: :
|
| |
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- LOIZOS NICK ET AL: "Targeting the platelet-derived growth factor receptor a with a
neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: Implications
as a potential therapeutic target" MOLECULAR CANCER THERAPEUTICS, AMERICAN ASSOCIATION
OF CANCER RESEARCH, US, vol. 4, no. 3, 1 March 2005 (2005-03-01), pages 369-379, XP009104391
ISSN: 1535-7163
- SHEN JUQUN ET AL: "Single variable domain-IgG fusion. A novel recombinant approach
to Fc domain-containing bispecific antibodies" JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN
SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM, US, vol. 281, no. 16, 21 April 2006
(2006-04-21), pages 10706-10714, XP002478591 ISSN: 0021-9258 [retrieved on 2006-02-15]
- DEEVI DHANVANTHRI S ET AL: "Inhibition of human osteosarcoma xenograft growth by anti-Platelet
derived growth factor receptor alpha antibody, IMC-3G3, alone and in combination with
chemotherapy" PROCEEDINGS OF THE ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR CANCER
RESEARCH, NEW YORK, NY, US, vol. 47, 5 April 2006 (2006-04-05), page 877, XP001538531
ISSN: 0197-016X
- BOARD R ET AL: "Platelet-derived growth factor receptor (PDGFR): A target for anticancer
therapeutics" DRUG RESISTANCE UPDATES, CHURCHILL LIVINGSTONE, EDINBURGH, GB, vol.
8, no. 1-2, 1 February 2005 (2005-02-01), pages 75-83, XP004919316 ISSN: 1368-7646
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