(19)

(11)

EP 2 104 512 A2

(12)

(88) Date of publication A3: 22.05.2009 (43) Date of publication: 30.09.2009 Bulletin 2009/40 (21) Application number: 07874553.6 (22) Date of filing: 21.12.2007

(51) International Patent Classification (IPC):  A61K 39/09(2006.01) G01N 33/569(2006.01) A61K 39/40(2006.01) (86) International application number: PCT/IB2007/004637 (87) International publication number: WO 2008/152448 (18.12.2008 Gazette 2008/51)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR (30) Priority: 21.12.2006 US 876156 P 02.11.2007 US 985111 P (71) Applicant: Emergent Product Development UK Limited Wokingham, Berkshire RG41 5TU (GB)	(72) Inventors: REDFERN, Mark Calcot Reading Berks RG31 7PD (GB) HARRIES, Helen Caversham Berkshire RG4 7HL (GB) BEDWELL, Joanne Burghfield Berks RG30 3ST (GB) CHATFIELD, Steven, Neville Park Langley Beckenham BR3 3AE (GB) (74) Representative: Jappy, John William Graham  Gill Jennings & Every LLP Broadgate House 7 Eldon Street London EC2M 7LH 7 Eldon Street London EC2M 7LH (GB)