(19)
(11) EP 2 104 674 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
02.10.2013 Bulletin 2013/40

(45) Mention of the grant of the patent:
01.05.2013 Bulletin 2013/18

(21) Application number: 07845534.2

(22) Date of filing: 15.11.2007
(51) International Patent Classification (IPC): 
C07D 333/40(2006.01)
A61K 31/381(2006.01)
C07D 333/38(2006.01)
 A61P 31/12(2006.01)
C07D 409/12(2006.01)
(86) International application number:
PCT/CA2007/002064
(87) International publication number:
WO 2008/058393 (22.05.2008 Gazette 2008/21)

(54)

THIOPHENE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS

THIOPHENANALOGA ZUR BEHANDLUNG ODER PRÄVENTION VON FLAVIVIRUS-INFEKTIONEN

ANALOGUES DU THIOPHÈNE POUR LE TRAITEMENT OU LA PRÉVENTION D'INFECTIONS PAR UN FLAVIVIRUS

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR
Designated Extension States:
AL BA HR MK RS

(30) Priority: 15.11.2006 US 858939 P

(43) Date of publication of application:
30.09.2009 Bulletin 2009/40

(60) Divisional application:
12181993.2 / 2559691
12181998.1 / 2559692

(73) Proprietor: Vertex Pharmaceuticals (Canada) Incorporated
Laval, Québec H7V 4A7 (CA)

(72) Inventors:
  • CHAN CHUN KONG, Laval
    Kirkland, Québec H9J 3X8 (CA)
  • KUMAR DAS, Sanjoy
    Pierrefonds, Québec H9H 2G2 (CA)
  • POISSON, Carl
    Montreal, Québec H2M 1B5 (CA)
  • YANNOPOULOS, Constantin G.
    Notre-Dame de l'Ile Perrot, Québec, CA J7Z 8X3 (CA)
  • FALARDEAU, Guy
    Laval, Québec J7V 8X3 (CA)
  • VAILLANCOURT, Louis
    Mascouche, Québec J7K 3Z6 (CA)
  • DENIS, Réal
    Laval, Québec H7J 1C7 (CA)

(74) Representative: HOFFMANN EITLE 
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München
81925 München (DE)


(56) References cited: : 
WO-A-02/100851
WO-A2-2006/072348
 WO-A-2006/072347
   
       
    Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).