(19)

(11)

EP 2 107 910 A2

(12)

(88) Date of publication A3: 09.04.2009 (43) Date of publication: 14.10.2009 Bulletin 2009/42 (21) Application number: 07853378.3 (22) Date of filing: 14.12.2007

(51) International Patent Classification (IPC):  A61K 47/48(2006.01) A61K 41/00(2006.01) (86) International application number: PCT/US2007/025551 (87) International publication number: WO 2008/076333 (26.06.2008 Gazette 2008/26)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR (30) Priority: 13.12.2006 US 874572 P 24.01.2007 US 897096 P 09.11.2007 US 2752 (71) Applicant: Insert Therapeutics, Inc. Pasadena, CA 91106 (US)	(72) Inventors: DAVIS, Mark E. Pasadena, CA 91105 (US) HWANG, Jungyeon Northridge, CA 91325 (US) KE, Tianyi Arcadia, CA 91006 (US) LIM, Jing-jou San Diego, CA 92122 (US) SCHLUEP, Thomas La Crescenta, CA 91214 (US) (74) Representative: Adams, Harvey Vaughan John  Mathys & Squire LLP 120 Holborn London EC1N 2SQ London EC1N 2SQ (GB)