(19)
(11) EP 2 111 413 A2

(12)

(88) Date of publication A3:
19.02.2009

(43) Date of publication:
28.10.2009 Bulletin 2009/44

(21) Application number: 08729968.1

(22) Date of filing: 15.02.2008
(51) International Patent Classification (IPC): 
C07K 14/435(2006.01)
(86) International application number:
PCT/US2008/054081
(87) International publication number:
WO 2008/101160 (21.08.2008 Gazette 2008/34)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

(30) Priority: 16.02.2007 US 890428 P

(71) Applicant: Genentech, Inc.
South San Francisco, CA 94080 (US)

(72) Inventors:
  • APPLETON, Brent, A.
    San Francisco, California 94121 (US)
  • RUNYON, Steven, T.
    Oakland, California 94608 (US)
  • SIDHU, Sachdev, S.
    Toronto, Ontario M5S 2M3 (CA)
  • SKELTON, Nicholas, J.
    San Mateo, California 94401 (US)
  • WIESMANN, Christian
    Brisbane, California 94005 (US)
  • ZHANG, Yingnan
    Brisbane, California 94005 (US)

(74) Representative: Casley, Christopher Stuart et al
Mewburn Ellis LLP 33 Gutter Lane
London EC2V 8AS
London EC2V 8AS (GB)

   


(54) HTRA1-PDZ AND HTRA3-PDZ MODULATORS