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(11)

EP 2 115 465 A2

(12)

(88) Date of publication A3: 21.08.2008 (43) Date of publication: 11.11.2009 Bulletin 2009/46 (21) Application number: 07868028.7 (22) Date of filing: 26.12.2007

(51) International Patent Classification (IPC):  G01N 33/53(2006.01) A01N 37/18(2006.01) G01N 33/567(2006.01) A61K 38/00(2006.01) (86) International application number: PCT/US2007/026315 (87) International publication number: WO 2008/079400 (03.07.2008 Gazette 2008/27)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR (30) Priority: 22.12.2006 US 876821 P 16.11.2007 US 985745 (71) Applicants: The Regents of the University of California Oakland, CA 94607-5200 (US) Department of Veterans Affairs Washington, DC 20420 (US)	(72) Inventors: MURRAY, Samuel S. Saugus, CA 91350 (US) MURRAY, Elsa J. Saugus, CA 91350 (US) BEHNAM, Keyvan Red Bank, NJ 07701 (US) WANG, Jeffrey C. Sherman Oaks, CA 91403 (US) (74) Representative: Hill, Justin John et al McDermott Will & Emery UK LLP 7 Bishopsgate London EC2N 3AR London EC2N 3AR (GB)