(19)

(11)

EP 2 117 540 A1

(12)

(43) Date of publication: 18.11.2009 Bulletin 2009/47 (21) Application number: 08717208.6 (22) Date of filing: 28.02.2008

(51) International Patent Classification (IPC):  A61K 31/4164(2006.01) C07D 235/06(2006.01) C07D 405/12(2006.01) A61P 25/28(2006.01) C07D 233/54(2006.01) C07D 403/12(2006.01) C07D 417/12(2006.01) (86) International application number: PCT/EP2008/052411 (87) International publication number: WO 2008/104580 (04.09.2008 Gazette 2008/36)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR (30) Priority: 01.03.2007 US 892265 P 14.03.2007 US 685881 (71) Applicant: Probiodrug AG 06120 Halle/Saale (DE)	(72) Inventors: SCHILLING, Stephan 06130 Halle / Saale (DE) CYNIS, Holger 06110 Halle / Saale (DE) HOFFMANN, Torsten 06114 Halle / Saale (DE) DEMUTH, Hans-Ulrich 06120 Halle / Saale (DE) (74) Representative: Hoffmann, Matthias  Probiodrug AG Weinbergweg 22 06120 Halle/Saale 06120 Halle/Saale (DE)