(19)

(11)

EP 2 118 321 A2

(12)

(88) Date of publication A3: 19.02.2009 (43) Date of publication: 18.11.2009 Bulletin 2009/47 (21) Application number: 08741999.0 (22) Date of filing: 06.02.2008

(51) International Patent Classification (IPC):  C12Q 1/68(2006.01) C07H 21/04(2006.01) (86) International application number: PCT/US2008/001529 (87) International publication number: WO 2008/123901 (16.10.2008 Gazette 2008/42)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR (30) Priority: 06.02.2007 US 899615 P 09.07.2007 US 948565 P (71) Applicant: Genizon Biosciences Montreal, Québec H4T 2C7 (CA)

(72) Inventors: BELOUCHI, Abdelmajid Ville St.-laurent, Québec H4T 2C7 (CA) RAELSON, John Verner Ville St.-laurent, Québec H4T 2C7 (CA) PAQUIN, Bruno Ville St.-laurent, Québec H4T 2C7 (CA) BRIAND, Sandy Ville St.-laurent, Québec H4T 2C7 (CA) DUBOIS, Daniel Ville St.-laurent, Québec H4T 2C7 (CA) VAN EERDEWEGH, Paul Ville St.-laurent, Québec H4T 2C7 (CA) SEGAL, Jonahan Ville St.-laurent, Québec H4T 2C7 (CA) LITTLE, Randall David Ville St.-laurent, Québec H4T 2C7 (CA) KEITH, Tim Ville St.-laurent, Québec H4T 2C7 (CA) (74) Representative: Bentham, Andrew et al J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)