(19)

(11)

EP 2 121 022 A2

(12)

(88) Date of publication A3: 28.08.2008 (43) Date of publication: 25.11.2009 Bulletin 2009/48 (21) Application number: 07867908.1 (22) Date of filing: 19.12.2007

(51) International Patent Classification (IPC):  A61K 45/06(2006.01) A61K 31/4545(2006.01) A61K 31/4704(2006.01) A61P 11/02(2006.01) (86) International application number: PCT/US2007/026107 (87) International publication number: WO 2008/079312 (03.07.2008 Gazette 2008/27)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR Designated Extension States: AL BA HR MK RS (30) Priority: 22.12.2006 US 871661 P (71) Applicant: Schering Corporation Kenilworth, NJ 07033-0530 (US)	(72) Inventors: DANZIG, Melvyn Richard Morganville, New Jersey 07751 (US) DOWN, Gerald Robert Brian Pierrefonds, Quebec H9H 2B8 (CA) (74) Representative: HOFFMANN EITLE  Patent- und Rechtsanwälte Arabellastrasse 4 81925 München 81925 München (DE)