(19)

(11)

EP 2 121 745 A2

(12)

(88) Date of publication A3: 26.03.2009 (43) Date of publication: 25.11.2009 Bulletin 2009/48 (21) Application number: 08709645.9 (22) Date of filing: 26.02.2008

(51) International Patent Classification (IPC):  C07K 14/705(2006.01) G01N 33/68(2006.01) G01N 33/574(2006.01) (86) International application number: PCT/GB2008/050125 (87) International publication number: WO 2008/104804 (04.09.2008 Gazette 2008/36)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR (30) Priority: 26.02.2007 US 903510 P 26.02.2007 US 903509 P 05.06.2007 WO PCT/EP2007/055537 25.02.2008 WO PCT/GB2008/050124 (71) Applicant: Oxford Genome Sciences (UK) Limited Oxford, Oxfordshire OX2 0JB (GB)	(72) Inventors: ROHLFF, Christian Oxford, Oxfordshire OX14 4RY (GB) STAMPS, Alasdair Oxford, Oxfordshire OX14 4RY (GB) (74) Representative: Winter, Christopher Spencer  Sagittarius IP Taylor House 39 High Street Marlow Buckinghamshire SL7 1AF Marlow Buckinghamshire SL7 1AF (GB)