(19)
(11) EP 2 125 723 A1

(12)

(43) Date of publication:
02.12.2009 Bulletin 2009/49

(21) Application number: 08727502.0

(22) Date of filing: 10.01.2008
(51) International Patent Classification (IPC): 
C07D 209/42(2006.01)
C07D 405/14(2006.01)
A61P 27/00(2006.01)
 C07D 405/12(2006.01)
A61K 31/404(2006.01)
C07D 401/06(2006.01)
(86) International application number:
PCT/US2008/050695
(87) International publication number:
WO 2008/089015 (24.07.2008 Gazette 2008/30)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

(30) Priority: 11.01.2007 US 884470 P

(71) Applicant: ALLERGAN, INC.
Irvine CA 92612 (US)

(72) Inventors:
  • BEARD, Richard, L.
    Newport Beach, CA 92660 (US)
  • YUAN, Haiqing
    Irvine, CA 92606 (US)

(74) Representative: HOFFMANN EITLE 
Patent- und Rechtsanwälte Arabellastrasse 4
81925 München
81925 München (DE)

   


(54) 6-SUBSTITUTED INDOLE-3-CARBOXYLIC ACID AMIDE COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR ANTAGONIST BIOLOGICAL ACTIVITY